Building photo of 5000 Shoreline
South San Francisco, CA

5000 Shoreline

About the Building

5000 Shoreline is a premier life science conversion project located directly on the Bayfront in South San Francisco, the birthplace of biotech, surrounded by some of the country’s most innovative companies making breakthroughs in scientific and technological research and development. With its robust building systems, large floorplates and flexible configurations, this Class A building stands ready to accommodate all life science users.

  • 3 Floors
  • 143,000 SF Rentable Area
An aerial view of a group of buildings with a park and walkways connecting to an inner parking lot aligned along the waterfont


    • Conference center
    • Electric vehicle (EV) charging stations (4)
    • Fitness center
    • Loading dock
    • Parking
    • Passenger elevators (2)
    • Service elevators (2)
    • Showers

Available Spaces

Floor plan of Partial 1st Floor, Suite 101, 5000 Shoreline

Suite 101

Partial 1st Floor




Floor plan of Partial 2nd Floor, Suite 200, 5000 Shoreline

Suite 200

Partial 2nd Floor




Floor plan of Partial 2nd Floor, Suite 201, 5000 Shoreline

Suite 201

Partial 2nd Floor




Floor plan of Partial 2nd Floor, Suite 202, 5000 Shoreline

Suite 202

Partial 2nd Floor





The Property sits in the Sierra Point life science cluster of South San Francisco adjacent to the San Francisco Bay Trail, easily accessible via Highway 101 and Interstate 280, and within a 10-minute drive to BART, Caltrain and SFO.

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For Leasing Inquiries

Logo for CBRE
A bird's eye view on the San Francisco downtown area during sunset

About DivcoWest

Founded in 1993, DivcoWest, a DivCore Capital company, is a vertically integrated real estate investment firm headquartered in San Francisco, with offices in Austin, Cambridge, Los Angeles, Menlo Park, Washington DC, and New York City. Known for long-standing relationships and experience across the risk-spectrum in innovation markets, DivcoWest combines entrepreneurial spirit with an institutional approach to commercial real estate. DivcoWest aims to create environments that inspire ingenuity, promote growth, and enhance health and well-being. DivcoWest’s real estate portfolio currently includes existing and development properties in the office, R&D, lab, industrial, retail, and multifamily spaces - primarily throughout the United States. Visit us at